Abacavir (A) + Lamivudine (B)

Generic name: Abacavir (A) + Lamivudine (B)

Possible Side Effects

Headache is a common side effect of Abacavir plus Lamivudine.
Nausea and sometimes vomiting may occur.
Diarrhea or stomach upset can happen.
Dizziness or feeling tired or weak is sometimes reported.
Rash can occur; most are mild but should be checked if widespread or persistent.
Sleep problems or vivid dreams have been reported by some people.
Rare but serious reactions include signs of abacavir hypersensitivity (fever, rash, nausea, vomiting, diarrhea, trouble breathing); seek urgent medical care immediately if these occur.
In India, contact your doctor promptly or go to a government hospital, primary health centre, or district hospital for evaluation if you develop severe or unexpected side effects.
Always consult a qualified doctor or local healthcare provider in India for personalized medical advice and before making any changes to treatment.

Warnings / Contraindications

Abacavir/lamivudine can cause a serious hypersensitivity reaction in some people, especially if they have the HLA-B*57:01 gene; screening is recommended before starting where available.
Watch for fever, rash, tiredness, nausea, vomiting, diarrhea, or breathing problems—these may signal hypersensitivity and require stopping the medicine.
If hypersensitivity is suspected, do not restart Abacavir/Lamivudine; consult a doctor promptly and discontinue the drug.
People with significant liver disease or a history of lactic acidosis on nucleoside medicines should use this combination only under close medical supervision.
Lamivudine is cleared by the kidneys, so people with kidney problems may need dose adjustments or alternative regimens under a doctor’s guidance.
There can be interactions with other medicines, including other HIV drugs and some supplements; tell your doctor or pharmacist about all medicines you take.
Pregnant or breastfeeding individuals should use this combination only under medical guidance in India.
Guidelines can vary by country; always follow your doctor’s advice and local Indian guidelines, and check with a doctor or pharmacist in India before starting, stopping, or changing any treatment.