5-aminosalicylic acid (Mesalazine/Mesalaine)

Generic name: (Mesalazine/Mesalaine)

Possible Side Effects

Common side effects of 5-aminosalicylic acid (mesalazine) include gastrointestinal symptoms such as nausea, vomiting, abdominal pain, and diarrhea.
Headache and dizziness are also commonly reported.
Skin reactions like rash, itching, or hives may occur in some people.
Rare liver-related effects (changes in liver enzymes or hepatitis) and pancreatitis have been reported.
Kidney involvement, including changes in kidney function or interstitial nephritis, can occur rarely.
Flushing, fever, or general malaise may be seen in some individuals.
Serious side effects must be discussed with a doctor immediately—seek urgent care if you have severe abdominal pain, persistent vomiting, yellowing of the eyes or skin, dark urine, severe rash with breathing difficulties, or signs of an allergic reaction.
Always consult a qualified doctor or local healthcare provider in India for personal medical decisions or emergencies.

Warnings / Contraindications

- Do not use if you have a known allergy to mesalazine or to other salicylates (for example aspirin).
- Use with caution if you have kidney or liver disease; mesalazine can affect kidney function or liver enzymes and may require monitoring.
- If you are pregnant or breastfeeding, discuss with your doctor; decisions depend on risk-benefit in your situation.
- Tell your doctor or pharmacist about all medicines you take (including NSAIDs like ibuprofen/diclofenac and anticoagulants) as interactions can occur.
- Rare but serious effects can include pancreatitis, severe allergic reactions, blood disorders, or worsening kidney injury; seek urgent care if you develop severe stomach pain, yellowing of skin/eyes, dark urine, swelling, or widespread rash.
- Do not change or stop treatment without medical advice; some people need monitoring or dose adjustments.
- Availability and formulations vary in India—consult a doctor or pharmacist at your local clinic, PHC, or government hospital for personalized guidance.

Medication information is simplified and may not cover all uses, precautions, or side effects. Always follow your doctor's instructions and read the official medication guide.